Aromatase Inhibitors in Premenopausal Breast Cancer Patients With Chemotherapy-Induced Ovarian Failure

Inclusion Criteria:

To be eligible for this study:

1. You must be at least 18 years of age and not older than 60 years of age

2. You have breast cancer which was confined to the breast and lymph nodes under the
arm, and have no evidence of cancer elsewhere

3. You must have had surgical removal of your tumor, and if indicated, radiation therapy
must have been completed or planned

4. Your tumor must express estrogen and/or progesterone receptors

5. You must have had a menstrual period within 6 months before starting chemotherapy for
your breast cancer.

6. You must have been treated with a chemotherapy regimen that includes cyclophosphamide
(Cytoxan). Your menstrual periods must have stopped for at least 8 weeks starting
during or after chemotherapy.

Exclusion Criteria:

You are not eligible to participate in this study if:

1. Your ovaries have been surgically removed, treated with radiation therapy, or if you
are taking medications (Zoladex™ or Lupron™) to block the function of your ovaries.