Optical Sensor for Photodynamic Detection of Oral Pathology

Trial Information

Optical Sensor for Photodynamic Detection of Oral Pathology

This study determined the change in the optical properties of oral tissues, and combine
these with conventional semiquantitative histopathological to have information of the oral
pathology.

The study to determine the absorption and reflection spectra of healthy and pathological
oral tissues and to correlate these with oral pathology. Rationale is that tissue
architecture, components, metabolic processes and vasculature change with the onset and
progression of pathology. Each of these factors has optical signatures that detected
non-invasively.

A soft small fiberoptic pen shape sensor with fiberoptic-based spectrographic system place
in selective oral cavity. Six measurements and image will be taking within approximate 5
minutes.

The possible risks and/or discomforts associated with the procedures described in this study
include some discomfort of having the optical tool placed in the mouth the device will be
removed immediately. There may also be risks to participating that are currently
unforeseeable.

There are no direct benefit but potential benefit to society by helping to develop new tools
for early detection, monitoring, screening for oral pathology