Inclusion Criteria:

- Patients are required to have pathologically confirmed adenocarcinoma or squamous
cell carcinoma of the esophagus or gastroesophageal junction

- Patients may have celiac adenopathy

- There must be no evidence of distant organ metastases

- No prior chemotherapy or radiation for esophageal cancer

- Patients must be > 18 years of age, and non pregnant

- Patients must have an ANC > 1,500/ul, platelets > 100,000/ul, creatinine < 2.0 and
bilirubin < 1.5 x ULN-ECOG performance status 0-1.

- Female patients, must either be not of child bearing potential or have a negative
pregnancy test within 14 days of starting study treatment. Patients are considered
not of child bearing potential if they are surgically sterile (they have undergone a
hysterectomy, bilateral tubal ligation, or bilateral oophorectomy) or they are
postmenopausal. Pregnant or lactating females are not eligible

- No contraindications to esophagectomy

- Signed informed consent

Exclusion Criteria:

- Active or uncontrolled infection

- Patients must not have other coexistent medical condition that would preclude
protocol therapy.

- Any concurrent chemotherapy not indicated in the study protocol or any other
investigational agent(s).