Inclusion Criteria

Criteria:

- Biopsy-proven adenocarcinoma of the prostate meeting the following criteria:
organ-confined disease; treatable by prostatectomy

- PSA < 50 ng/mL

- ECOG performance status (PS) 0-1 or Karnofsky PS 70-100%

- Bilirubin normal

- AST and ALT normal

- Creatinine normal

- Fertile patients must use effective contraception

- No uncontrolled intercurrent illness including, but not limited to, any of the
following: ongoing or active infection; symptomatic congestive heart failure;
unstable angina pectoris; cardiac arrhythmia; psychiatric illness or social
situations that would limit study compliance

- No history of allergic reactions attributed to compounds of similar chemical or
biologic composition to green tea extract

- No prior therapy for prostate cancer (i.e., hormone therapy, radiation therapy, or
surgery)

- No systemic treatment (chemotherapy) and/or radiation therapy for any malignancy
within the past 5 years (excluding nonmelanoma skin cancer or cancer confined to
organs with surgical removal as the only treatment)

- No regular tea consumption (> 6 servings of hot tea or 12 servings of iced tea or
equivalent combination per week) within the past month

- No other concurrent investigational agents

- No other concurrent consumption of tea or tea-derived products from green, black, or
oolong tea