Trial Information

Improving Systems for Colorectal Cancer Screening

OBJECTIVES:

Primary

- Determine whether rates of colorectal cancer (CRC) screening can be increased among
average-risk adults by using patient-specific, active, electronic, clinical reminders
for primary care physicians during office visits and mailed reminders and fecal occult
blood test cards for patients.

Secondary

- Calculate baseline rates of CRC screening, in terms of patient demographic
characteristics, primary care physician, and practice group, by using computerized
clinical information systems to identify patients due for screening.

- Assess baseline rates of CRC screening among patients insured by different health
plans.

- Determine whether the impact of the interventions is related to efforts by health plans
to promote CRC screening.

- Evaluate patients' willingness to use a validated web-based tool to estimate their
personal risk of CRC.

OUTLINE: This is a randomized, controlled study. Patients are randomized to 1 of 2 arms
(arms I or III). Physicians are randomized to 1 of 2 arms (arms II or IV).

- Arm I: Patients receive mailed reminders for colorectal cancer (CRC) screening.
Patients also receive fecal occult blood testing (FOBT) instructions and cards.
Patients who remain overdue for screening at 6 months after the initial mailing receive
a follow-up letter reminding them of their need to be screened. Patients who return
positive FOBT cards undergo colonoscopy within 1 month. The patient's primary care
physician may receive computerized screening reminders at the time of the patient's
office visit and may order CRC screening tests online.

- Arm II: Patients receive no mailings. The patient's primary care physician may receive
computerized screening reminders at the time of the patient's office visit and may
order CRC screening tests online.

- Arm III: Patients receive mailed reminders for CRC screening. The patient's primary
care physician may order CRC screening tests online, but will not receive active
computerized reminders. Patients also receive FOBT instructions and cards. Patients who
remain overdue for screening at 6 months after the initial mailing receive a follow-up
letter reminding them of their need to be screened. Patients who return positive FOBT
cards will be scheduled to undergo colonoscopy within 1 month.

- Arm IV: Patients receive no mailings. The patient's primary care physician may order
CRC screening tests online, but will not receive active computerized reminders.

Patients are followed for 15 months to determine screening rates.

PROJECTED ACCRUAL: A total of 21,860 patients will be accrued for this study.