Effect of Esomeprazole on the Pharmacokinetics of BMS-275183 in Patients With Advanced Malignancies
Phase 1
18 Years
N/A
18 Years
N/A
Not Enrolling
Both
Cancer
Both
Cancer
Trial Information
Effect of Esomeprazole on the Pharmacokinetics of BMS-275183 in Patients With Advanced Malignancies
Inclusion Criteria:
- Advanced cancers excluding cancers within the blood
- Adequate kidney and liver function
- > = 4 weeks from last course of chemotherapy
Exclusion Criteria:
- Inability to swallow capsules
- Other active medical disorder
- Abnormal heart function or use of drugs that affect the heart
Type of Study:
Interventional
Study Design:
Allocation: Randomized, Endpoint Classification: Safety Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
Outcome Measure:
To assess the safety of taking Nexium in combination with oral taxane and the effect this combination has on oral taxane's exposure levels in the body.
Authority:
United States: Food and Drug Administration
Study ID:
CA165-030
NCT ID:
NCT00332748
Start Date:
December 2006
Completion Date:
Related Keywords:
- Cancer
Name | Location |
|---|---|
| Local Institution | Louisville, Kentucky |
| Local Institution | Las Vegas, Nevada |
| Local Institution | Newark, Delaware |
