Bio-Behavioral Lung Cancer Prevention Program

Inclusion Criteria:

Eligible smokers will be those currently smoking at least 10 cigarettes a day.

Exclusion Criteria:

Exclusionary criteria are: planning a pregnancy, pregnancy, lactating, seizure disorder,
history of head trauma or prior seizure, family history of a seizure disorder, brain (or
CNS) tumor, history of or currently diagnosed with bulimia or anorexia nervosa, diabetes
treated with oral hypoglycemics or insulin, excessive use of alcohol or alcoholism,
current addiction to opiates, cocaine, or stimulants, use of other drugs containing
bupropion (e.g., Wellbutrin, Wellbutrin SR), allergy to bupropion, currently taking
particular medications (e.g., monoamine oxidase inhibitor, antipsychotics,
antidepressants, theophylline, systemic steroids, over-the-counter stimulants and
anorectics), recently taken a MAOI (less than 14 days) or a recent discontinuation of a
benzodiazepine.