Trial Information

Resveratrol for Patients With Colon Cancer

Patients will be treated with a two-week course of resveratrol. The initiation of the
treatment will be approximately 14 days before standard of care surgical resection of tumor.
Resveratrol will be ingested as 20 mg pills or in the form of freeze-dried grape extract
which is prepared by the California Table Grape Commission used under GMP guidelines for
human consumption.

The first two patients receiving resveratrol will be treated at a dose of 20 mg/day, the
third and fourth patients at a dose of 80 mg/day, and the fifth and sixth patients with a
dose of 160 mg/day. All patients receiving grape extract will receive 125 mg/day that will
have to be mixed with one 8 oz glass of water. There will be no dose adjustments. If a
patient has any side effects which are attributed to the resveratrol, it will be
discontinued.