or
forgot password

Chemotherapy Plus Local Surgical Treatment in Children With Intraocular Germ-Line Retinoblastoma


Phase 2
N/A
N/A
Open (Enrolling)
Both
Retinoblastoma, Retinal Neoplasms

Thank you

Trial Information

Chemotherapy Plus Local Surgical Treatment in Children With Intraocular Germ-Line Retinoblastoma

Inclusion Criteria


Eligibility Criteria:

- Initial clinical diagnosis of Retinoblastoma, with Bilateral tumors, OR Unilateral
tumor with hope for salvage of vision AND Multiple primary tumors, or positive family
history for retinoblastoma, or age < 12 months

- No prior antitumor therapy (except enucleation of one eye)

- At least one tumor exceeds 6 mm in diameter

- No evidence of dissemination outside the globe

- Signed IRB-approved informed consent

- Patient/family available for follow-up

Type of Study:

Interventional

Study Design:

Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Outcome Measure:

To determine if a multimodal approach can provide durable control of retinoblastoma and specifically:

Principal Investigator

Stewart Goldman, MD

Investigator Role:

Principal Investigator

Investigator Affiliation:

Ann & Robert H Lurie Children's Hospital of Chicago

Authority:

United States: Institutional Review Board

Study ID:

CNS 0294

NCT ID:

NCT00179920

Start Date:

April 1996

Completion Date:

September 2006

Related Keywords:

  • Retinoblastoma
  • Retinal Neoplasms
  • Neoplasms
  • Retinoblastoma
  • Retinal Neoplasms

Name

Location
Children's Memorial Hospital Chicago, Illinois  60614