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Alopecia Areata Registry and Immunogenetic Mechanisms


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Alopecia Areata

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Trial Information

Alopecia Areata Registry and Immunogenetic Mechanisms


The purpose of this registry is to collect patient epidemiology data as well as to provide
samples that can be used for understanding the pathogenesis of AA, especially related to its
genetic basis as a complex trait. There are three ways one can assess which genes are
important: association studies in unrelated individuals, identify by descent in sib-pairs,
and linkage or transmission by descent in multiplex families.


Inclusion Criteria:



- All patients with AA, children and adults, who have been diagnosed by a
dermatologist, who is an expert in the field of alopecia. Subtypes that are
allowable are alopecia universalis, alopecia totalis, patchy persistent alopecia or
transient mild alopecia.

- Family members, related by blood, of these patients (preferably sib-pairs plus
parents and multiplex families).

- Age matched controls from spouses or clinic patients

Exclusion Criteria:

- A person under the age of 18 years not accompanied by parent or guardian.

- A person who is unable to comprehend the informed consent and sign the consent form.

Type of Study:

Observational

Study Design:

Observational Model: Case Control, Time Perspective: Retrospective

Principal Investigator

Maria Hordinsky, MD

Investigator Role:

Principal Investigator

Investigator Affiliation:

University of Minnesota - Clinical and Translational Science Institute

Authority:

United States: Institutional Review Board

Study ID:

0107M05422

NCT ID:

NCT00177073

Start Date:

September 2001

Completion Date:

December 2014

Related Keywords:

  • Alopecia Areata
  • Alopecia
  • Alopecia Areata

Name

Location
University of Minnesota Minneapolis, Minnesota  55455