Trial Information

HLA Sensitization Following Major Cortical Allograft Bone Procedures

Patients who have bone cancer often have the cancerous bone removed by surgery and replaced
with a piece of bone taken from a donor (a person who donates parts of their body to be used
for transplants after their death). However, sometimes this replacement bone does not heal
together with the patient's bone. The reason the bone does not heal is not known but it is
thought that the patient's body may react to the donor bone by producing antibodies against
cells on the donor bone. The purpose of this study is to find out whether or not antibodies
to the donor bone are present in the blood of patients who receive the donor bone. You have
been asked to participate in this study because you are scheduled to undergo this type of
surgery.