A Phase II, Randomized, Placebo-Controlled, Double-Blind Study to Evaluate the Efficacy of Pertuzumab (rhuMAb 2C4) in Combination With Gemcitabine and the Effect of Tumor-Based HER2 Activation in Subjects With Platinum-Resistant Ovarian, Primary Peritoneal, or Fallopian Tube Cancer
Interventional
Primary Purpose: Treatment
To assess the efficacy and to evaluate the safety and tolerability of pertuzumab in combination with gemcitabine relative to gemcitabine in combination with placebo in subjects with platinum-resistant ovarian, primary peritoneal, or fallopian tube cancer
Virginia Patton, M.D.
Study Director
Genentech
United States: Food and Drug Administration
TOC3258g
NCT00096993
November 2004
August 2007
Name | Location |
---|---|
Arizona Cancer Center | Tucson, Arizona 85724 |
Carle Clinic Association | Urbana, Illinois 61801 |
Dana-Farber Cancer Institute | Boston, Massachusetts 02115 |
Cedars-Sinai Medical Center | Los Angeles, California 90048 |
Sutter Cancer Center | Sacramento, California 95816 |
Franklin Square Hospital Center | Baltimore, Maryland 21237 |
Carolinas Medical Center | Charlotte, North Carolina 28232-2861 |
North Idaho Cancer Center | Coeur d'Alene, Idaho 83814 |
Comprehensive Cancer Institute | Huntsville, Alabama 35801 |
Massachusetts General Hospital | Boston, Massachusetts 02114-2617 |
Center for Cancer And Hematologic Disease | Cherry Hill, New Jersey 08046 |
Greater Baltimore Medical Center | Baltimore, Maryland 21204 |
Hematology Oncology, P.C. | Stamford, Connecticut 06902 |
Integrated Community Oncology Network | Jacksonville Beach, Florida 32250 |
University of Chicago | Chicago, Illinois 60637 |
University of Kentucky | Lexington, Kentucky 40536-0098 |
University of California, Los Angeles | Los Angeles, California |
Sharp Healthcare | San Diego, California 92121 |
Indiana University | Indianapolis, Indiana 46202 |
Florida Hospital | Orlando, Florida 32803 |
Cancer Center of Kansas | Wichita, Kansas 67214 |
St. Luke's Mountain States Tumor Institute | Boise, Idaho 83712 |
Univ. of Alabama at Birmingham | Birmingham, Alabama 35233 |
Northwest Alabama Cancer Center | Muscle Shoals, Alabama 35661 |
Alta Bates Comp. Cancer Ctr | Berkeley, California 94704 |
California Cancer Crae, Inc | Greenbrae, California 94904 |
Ventura County Hematology Oncology Specialists | Oxnard, California 93030 |
Southern California Permanente Medical Group (Kaiser) | San Diego, California 92120 |
Norwalk Medical Group | Norwalk, Connecticut 06856 |
Memorial Health Univ. Med. Ctr. | Savannah, Georgia 31404 |
St. Vincent Hospital | Indianapolis, Indiana 46260 |
Wayne State Univ. Barbara Ann Karmanos Cancer Inst. | Detroit, Michigan 48201 |
Cooper Health System | Voorhees, New Jersey 08043 |
Pelvic Surgery Assoc. | Columbus, Ohio 43222 |
Ohio State University College of Medicaine | Columbus, Ohio 43210 |
Oklahoma Univ. Medical Center | Oklahoma City, Oklahoma 73104 |
Corvallis Clinic | Corvallis, Oregon 97330 |
Kaiser Permanente Northwest Division | Portland, Oregon 97227 |
Womens and Infants Hospital | Providence, Rhode Island 02905 |
Northern Virginia Pelvic Surgery Assoc. | Annandale, Virginia 22003 |
Carilion Gyn/Onc | Roanoke, Virginia 24014 |