A Phase III Randomized, Open-Label Study of CG1940 and CG8711 Versus Docetaxel and Prednisone in Patients With Metastatic Hormone-Refractory Prostate Cancer Who Are Chemotherapy-Naïve
Phase 3
18 Years
N/A
18 Years
N/A
Not Enrolling
Male
Prostate Cancer
Male
Prostate Cancer
Trial Information
A Phase III Randomized, Open-Label Study of CG1940 and CG8711 Versus Docetaxel and Prednisone in Patients With Metastatic Hormone-Refractory Prostate Cancer Who Are Chemotherapy-Naïve
Inclusion Criteria:
- Confirmed diagnosis of or clinical history consistent with adenocarcinoma of the
prostate
- Metastatic prostate cancer deemed to be unresponsive or refractory to hormone therapy
- Detectable metastases
- Any Gleason score
- ECOG performance status 0-2
Exclusion Criteria:
- Prior treatment with chemotherapy
- Prior Immunotherapy
- Prior treatment with gene therapy
- Significant cancer related pain
Type of Study:
Interventional
Study Design:
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
Outcome Measure:
Survival
Safety Issue:
No
Authority:
United States: Food and Drug Administration
Study ID:
G-0029
NCT ID:
NCT00089856
Start Date:
July 2004
Completion Date:
October 2008
Related Keywords:
- Prostate Cancer
- Prostate
- Cancer
- Metastatic
- Hormone-refractory
- GVAX
- Chemotherapy
- Taxotere
- Docetaxel
- Prednisone
- Vaccine
- Allogeneic cells
- Advanced Prostate Cancer
- Prostatic Neoplasms
Name | Location |
|---|---|
| Johns Hopkins University | Baltimore, Maryland 21205 |
| Mayo Clinic Scottsdale | Scottsdale, Arizona 85259 |
| University of Illinois at Chicago | Chicago, Illinois 60612 |
| Dakota Cancer Institute | Fargo, North Dakota 58103-4940 |
| Virginia Oncology Associates | Newport News, Virginia 23606 |
| Dartmouth-Hitchcock Medical Center | Lebanon, New Hampshire 03756 |
| Georgia Cancer Specialists | Decatur, Georgia 30033 |
| Louisiana Oncology Associates | Lafayette, Louisiana 70506 |
| University of Oklahoma | Oklahoma City, Oklahoma 73190 |
| Seattle Cancer Care Alliance | Seattle, Washington 98109 |
| Frederick Memorial Hospital Regional Cancer Therapy Center | Frederick, Maryland 21701 |
| Jacobi Medical Center | Bronx, New York 10461 |
| Mary Crowley Medical Research Center | Dallas, Texas 75246 |
| Integrated Community Oncology Network | Jacksonville Beach, Florida 32250 |
| Tyler Cancer Center | Tyler, Texas 75702 |
| Memorial Health Care System | Chattanooga, Tennessee 37404 |
| SUNY Upstate Medical University | Syracuse, New York 13210 |
| Deaconess Billings Clinic | Billings, Montana 59107-5100 |
| Arkansas Cancer Research Center | Little Rock, Arkansas 72205 |
| Providence Portland Medical Center | Portland, Oregon 97213-3635 |
| California Pacific Medical Center | San Francisco, California 94115 |
| Center for Urological Research | La Mesa, California 91942 |
| Cancer Centers of Florida | Orlando, Florida 32806 |
| Urological Associates Of Lancaster | Lancaster, Pennsylvania 17604-3200 |
| California Cancer Care | Greenbrae, California 94904 |
| Sharp Healthcare | San Diego, California 92121 |
| San Diego Cancer Center | Vista, California 92083 |
| Charleston Hematology Oncology | Charleston, South Carolina 29403 |
| Gabrail Cancer Center | Canton, Ohio 44718 |
| San Bernardino Urological Associates | San Bernardino, California |
| Compassionate Cancer Care medical Group, Inc. | Fountain Valley, California 92708 |
| Summit Medical Group/Overlook Oncology Center | Summit, New Jersey 07901 |
| Medical Oncology Associates | Kingston, Pennsylvania 18704 |
| UC Irvine Medical Center | Orange, California |
| Hematology Oncology Associates of the Treasure Coast | Port St. Lucie, Florida 34952 |
| The West Clinic | Memphis, Tennessee 38120 |
| Atlanta VAMC | Decatur, Georgia 30033 |
| West Michigan Regional Cancer and Blood Center | Ludington, Michigan 49431 |
| Lancaster Cancer Center, LTD | Lancaster, Pennsylvania 17605 |
| Alaska Clinical Research Center | Anchorage, Alaska 99508 |
| Cancer Center of Colorado Springs | Colorado Springs, Colorado 80907 |
| Columbia University Medical Center | New York, New York 10032 |
| The Don and Sybil Harrington Cancer Center | Amarillo, Texas 79106 |
| Southwestern Oncology Research Department | Bennington, Vermont 05201 |
| Straub Clinic & Hospital | Honolulu, Hawaii 96813 |
| Winship Cancer Institute, Emory University | Atlanta, Georgia 30322 |
| Central Alabama Oncology, LLC | Alabaster, Alabama 35007 |
| Palo Verde Hematology/Oncology | Glendale, Arizona 85304 |
| ACRC/Arizona Clinical Res. Ctr. Inc. | Tuscon, Arizona 85715 |
| Pacific Coast Hem Onc. Medical Group | Fountain Valley, California 92708 |
| Oncology Care Medical Associates | Montebello, California 90640 |
| Cancer Research & Prevention Center | Soquel, California 95073 |
| Univ. of Colorado Health Science Center | Aurora, Colorado 80045 |
| The Hope Clinic | Bristol, Connecticut 06010 |
| Urology Center of Grove Hill | New Britain, Connecticut 06052-1395 |
| Carl & Dorothy Bennett Cancer Center | Stamford, Connecticut 06902 |
| Boca Raton Community Hospital, Inc. | Boca Raton, Florida 33486 |
| Michael and Dianne Bienes Comprehensive Cancer Center, Holy Cross Hospital | Fort Lauderdale, Florida 33308 |
| Oncology-Hematology Group of South Florida/Advanced Medical Specialists | Miami, Florida 33176 |
| Urology Consultants | Safety Harbor, Florida 34695 |
| Peachtree Hematology Oncology Consultants, PC | Atlanta, Georgia 30309 |
| Central Georgia Cancer Care, P.C. | Macon, Georgia 31201 |
| Welborn Clinic Research Center | Evansville, Indiana 47713 |
| Fort Wayne Medical Oncology/Hematology Inc. | Fort Wayne, Indiana 46815 |
| William Beaumont Hospital, Cancer Clinical Trials Office | Royal Oak, Michigan 48073-6706 |
| Newland Medical Associates, P.C. | Southfield, Michigan 48075 |
| Hematology Oncology Consultants, Inc. | St. Louis, Missouri 63136 |
| Hematology/Oncology Centers of the Northern Rockies, P.C. | Billings, Montana 59101 |
| Omaha VA Medical Center | Omaha, Nebraska 68198-7680 |
| The Center for Cancer & Hematologic Disease | Cherry Hill, New Jersey 08003 |
| Hematology-Oncology Associates of Northern New Jersey | Morristown, New Jersey 07962 |
| Presbyterian Hospital/ Center for Cancer Research | Charlotte, North Carolina 28204 |
| Northwestern Carolina Hematology Oncology, PA | Hickory, North Carolina 28602 |
| Medcenter One Cancer Care / Odyssey Research | Bismarck, North Dakota 58501 |
| Cleveland Clinic Foundation, Taussig Cancer Center | Cleveland, Ohio 44195 |
| Urologic Surgery PC | Bala Cynwyd, Pennsylvania 19004 |
| University of Pittsburgh Cancer Center | Pittsburgh, Pennsylvania 15232 |
| Urology Specialists and Associates, P.A. | Dallas, Texas 75231 |
| Center for Oncology Research and Treatment PA | Dallas, Texas 75230 |
| Mobley Research Center | Houston, Texas 77024 |
| Urology San Antonio | San Antonio, Texas 78229 |
| Virginia Mason Medical Center Urology | Seattle, Washington 98101 |
