A Phase II Trial of Single-agent Cetuximab Dose Escalated to Rash in Patients With Persistent or Recurrent Epithelial Ovarian or Primary Peritoneal Carcinoma
To determine the overall response rate of cetuximab alone in subjects with ovarian or
primary peritoneal carcinoma who have persistent or recurrent disease following 1-2 previous
regimens of chemotherapy. Potential relationship between response, dose, and the occurence
of rash in the treatment of subjects who have stable disease after the initial 6 weeks of
treatment, time to progression, and 1 yr survival.
Interventional
Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
Overall response rate
Every six weeks
No
E-mail: ClinicalTrials@ ImClone.com
Study Chair
ImClone LLC
United States: Food and Drug Administration
CA225-046
NCT00082212
November 2004
June 2007
Name | Location |
---|---|
ImClone Investigational Site | New York, New York 10021 |
ImClone Investigational Site | Jacksonville, Florida 32207 |
ImClone Investigational Site | Philadelphia, Pennsylvania 19107 |
ImClone Investigational Site | Seattle, Washington 98104 |
ImClone Investigational Site | Birmingham, Alabama 35233 |