Inclusion Criteria

DISEASE CHARACTERISTICS:

- Histologically or cytologically confirmed non-small cell lung cancer (NSCLC) of 1 of
the following subtypes:

- Squamous cell carcinoma

- Adenocarcinoma (including bronchoalveolar cell)

- Large cell anaplastic carcinoma (including giant and clear cell carcinomas)

- Poorly differentiated/not otherwise specified NSCLC

- Stage IIIA (T1-2, N2, M0 or T3, N1-2, M0) or IIIB (T4, any N, M0 or any T, N2-3, M0)

- If the largest mediastinal node is < 2.0 cm in diameter and this is the basis
for stage III disease, then at least 1 of the nodes must be cytologically or
histologically positive

- Unresectable disease

- No totally resected tumors

- Tumors adjacent to a vertebral body allowed provided all gross disease can be
encompassed in the radiation boost field and the boost volume is limited to < 50% of
the ipsilateral lung volume

- Measurable disease

- Transudate, cytologically negative, non-bloody pleural effusions allowed provided the
tumor can be encompassed within a reasonable field of radiotherapy

- Pleural effusions seen on a chest CT scan are allowed provided they are not
visible on a chest x-ray and are too small to tap

- No asymptomatic or symptomatic brain metastases

PATIENT CHARACTERISTICS:

Age

- 18 and over

Performance status

- Zubrod 0-1

Life expectancy

- Not specified

Hematopoietic

- Absolute neutrophil count ≥ 1,500/mm^3

- Platelet count ≥ 100,000/mm^3

- Hemoglobin ≥ 9 g/dL (transfusion independent)

Hepatic

- Bilirubin ≤ 1.5 mg/dL

- SGOT or SGPT ≤ 3 times upper limit of normal (ULN)

- Alkaline phosphatase ≤ 2.5 times ULN

Renal

- Creatinine ≤ 2.0 mg/dL

Cardiovascular

- No significant history of cardiac disease

- No uncontrolled hypertension

- No unstable angina

- No uncompensated congestive heart failure

- No myocardial infarction within the past year

- No cardiac ventricular arrhythmias requiring medication

- LVEF normal by MUGA or echocardiogram

Pulmonary

- No history of interstitial pneumonitis

- No history of severe chronic obstructive pulmonary disease requiring 3 or more
hospitalizations within the past year

- FEV_1 ≥ 1,200 cc

- No active pulmonary infection unresponsive to conventional antibiotics

Other

- Not pregnant or nursing

- Negative pregnancy test

- Fertile patients must use effective contraception during and for 4 weeks after study
therapy

- Glucose ≤ 2 times ULN

- No more than 5% weight loss within the past 3 months

- No known allergy to murine proteins or Cremophor EL

- No neuropathy grade 2 or greater

- No other malignancy within the past 2 years except adequately treated basal cell or
squamous cell skin cancer, carcinoma in situ of the cervix, or other in situ cancers

PRIOR CONCURRENT THERAPY:

Biologic therapy

- No prior drugs that target the epidermal growth factor receptor pathway

- No prior chimerized monoclonal antibody therapy

- No other concurrent immunotherapy

- No concurrent colony-stimulating factors (i.e., filgrastim [G-CSF] and sargramostim
[GM-CSF])

- Concurrent epoetin alfa allowed

Chemotherapy

- No prior systemic chemotherapy

- No other concurrent chemotherapy

Endocrine therapy

- No concurrent hormonal therapy except hormones for non-disease-related conditions
(e.g., insulin for diabetes) or steroids for acute symptom management, adrenal
failure, septic shock, or as antiemetics

Radiotherapy

- No prior thoracic or neck radiotherapy

- No concurrent intensity-modulated radiotherapy

Surgery

- Recovered from prior exploratory thoracotomy

- No prior surgical resection of the present cancer

Other

- More than 30 days since prior participation in another clinical trial

- No concurrent participation in another clinical trial

- No other concurrent anticancer therapy

- No amifostine during or for 3 months after study radiotherapy