Inclusion Criteria

Low- or intermediate-grade NHL using the International Working Formulation, subtypes IWF
A-G:

Using the Updated REAL/WHO Classification, the following pathologic subtypes are eligible:

- Small lymphocytic lymphoma

- Lymphoplasmacytic lymphoma/immunocytoma

- Follicular lymphoma

- Diffuse large B-cell lymphoma

- Peripheral T-cell lymphoma, not otherwise characterized

Progression of disease following treatment with standard chemotherapy

Bi-dimensionally measurable disease

Performance Status: ECOG < = 2

Patients with mantle cell lymphoma or mycosis fungoides are not eligible

Patients with known history of CNS metastasis are not eligible