Lung Screening Study
55 Years
74 Years
Both
Lung Cancer
Trial Information
Lung Screening Study
OBJECTIVES: I. Compare the efficacy of screening spiral CT scan and screening chest x-ray in
detecting lung cancer in current or former smokers at high risk for lung cancer.
OUTLINE: This is a randomized, multicenter study of lung cancer screening. Patients are
randomized to one of two screening arms. Arm I: Patients undergo one spiral CT scan. Arm II:
Patients undergo one chest x-ray. Patients and their primary care physicians are notified of
test results within 3 weeks of the exam.
PROJECTED ACCRUAL: A total of 3,000 participants (1,500 per screening arm) will be accrued
for this study at six screening centers (500 per center) by October 31, 2000.
Inclusion Criteria
DISEASE CHARACTERISTICS: See General Eligibility Criteria
PATIENT CHARACTERISTICS: Age: 55 to 74 Patients with a cigarette smoking history of at
least 30 pack-years Current smoker OR Smoker who has quit smoking within the past 10 years
No known prior history of lung cancer
PRIOR CONCURRENT THERAPY: No concurrent therapy for any cancer except nonmelanomatous skin
cancer No prior removal of any portion of the lungs No concurrent participation in other
cancer screening trial, including PLCO No concurrent participation in a primary cancer
prevention trial other than a smoking cessation trial
Type of Study:
Interventional
Study Design:
Primary Purpose: Screening
Principal Investigator
John K. Gohagan, PhD, FACE
Investigator Role:
Study Chair
Investigator Affiliation:
National Cancer Institute (NCI)
Authority:
United States: Federal Government
Study ID:
CDR0000068258
NCT ID:
NCT00006382
Start Date:
August 2000
Completion Date:
Related Keywords:
- Lung Cancer
- non-small cell lung cancer
- small cell lung cancer
- Lung Neoplasms
Name | Location |
|---|---|
| University of Alabama Comprehensive Cancer Center | Birmingham, Alabama 35294 |
| Vincent T. Lombardi Cancer Research Center, Georgetown University | Washington, District of Columbia 20007 |
| University of Minnesota Cancer Center | Minneapolis, Minnesota 55455 |
| Washington University School of Medicine | Saint Louis, Missouri 63110 |
| Henry Ford Hospital | Detroit, Michigan 48202 |
| Marshfield Clinic | Marshfield, Wisconsin 54449 |
