Assessment of Health/Quality of Life in Survivors of Childhood Cancer
8 Years
20 Years
Both
Leukemia, Lymphoma, Unspecified Childhood Solid Tumor, Protocol Specific
Trial Information
Assessment of Health/Quality of Life in Survivors of Childhood Cancer
OBJECTIVES: I. Assess the validity and reliability of a quality of life questionnaire
(MM-QOL) that is being developed for patients with previously or currently treated childhood
cancers.
OUTLINE: This is a randomized, multicenter study. Patients are stratified according to age
(8-12 vs 13-20) and treatment (current vs previous). Patients are randomized to one of two
arms of the study. Arm I (Reliability): Patients will complete the same questionnaire two
weeks apart. (age 13-20 stratum closed as of 7/14/00) Arm II (Validity): Patients will
complete a study questionnaire plus a Child Health Questionnaire. Patients between ages 8-12
are interviewed and patients between ages 13-20 complete a written questionnaire.
PROJECTED ACCRUAL: A total of 716 patients (416 for arm I (208 for 8-12 age group and 208
for 13-20 age group) and 300 for arm II (150 for 8-12 age group and 150 for 13-20 age
group)) will be accrued for this study.
Inclusion Criteria
DISEASE CHARACTERISTICS: Prior or current diagnosis of any pediatric cancer Current
chemoradiotherapy (at least 2 months since start of therapy) OR At least 1 year since
prior treatment and in remission
PATIENT CHARACTERISTICS: Age: 8 to 20 Performance status: Not specified Life expectancy:
Not specified Hematopoietic: Not specified Hepatic: Not specified Renal: Not specified
PRIOR CONCURRENT THERAPY: Biologic therapy: Not specified Chemotherapy: See Disease
Characteristics Endocrine therapy: Not specified Radiotherapy: See Disease Characteristics
Surgery: Not specified
Type of Study:
Interventional
Study Design:
Allocation: Randomized
Principal Investigator
Smita Bhatia, MD, MPH
Investigator Role:
Study Chair
Investigator Affiliation:
Beckman Research Institute
Authority:
United States: Federal Government
Study ID:
CDR0000067920
NCT ID:
NCT00005881
Start Date:
April 2000
Completion Date:
Related Keywords:
- Leukemia
- Lymphoma
- Unspecified Childhood Solid Tumor, Protocol Specific
- recurrent childhood acute lymphoblastic leukemia
- childhood Burkitt lymphoma
- stage I childhood lymphoblastic lymphoma
- stage II childhood lymphoblastic lymphoma
- stage III childhood lymphoblastic lymphoma
- stage IV childhood lymphoblastic lymphoma
- recurrent childhood lymphoblastic lymphoma
- recurrent childhood acute myeloid leukemia
- childhood diffuse large cell lymphoma
- childhood immunoblastic large cell lymphoma
- unspecified childhood solid tumor, protocol specific
- childhood acute myeloid leukemia in remission
- stage II childhood Hodgkin lymphoma
- stage I childhood Hodgkin lymphoma
- stage III childhood Hodgkin lymphoma
- stage IV childhood Hodgkin lymphoma
- recurrent/refractory childhood Hodgkin lymphoma
- stage I childhood small noncleaved cell lymphoma
- stage I childhood large cell lymphoma
- stage II childhood small noncleaved cell lymphoma
- stage II childhood large cell lymphoma
- stage III childhood small noncleaved cell lymphoma
- stage III childhood large cell lymphoma
- stage IV childhood small noncleaved cell lymphoma
- stage IV childhood large cell lymphoma
- recurrent childhood small noncleaved cell lymphoma
- recurrent childhood large cell lymphoma
- Leukemia
- Lymphoma
- Lymphoma, Non-Hodgkin
Name | Location |
|---|---|
| Memorial Sloan-Kettering Cancer Center | New York, New York 10021 |
| University of Michigan Comprehensive Cancer Center | Ann Arbor, Michigan 48109-0752 |
| Children's Hospital of Philadelphia | Philadelphia, Pennsylvania 19104 |
| CCOP - Southern Nevada Cancer Research Foundation | Las Vegas, Nevada 89106 |
| CCOP - Christiana Care Health Services | Wilmington, Delaware 19899 |
| CCOP - Colorado Cancer Research Program, Inc. | Denver, Colorado 80209-5031 |
| CCOP - Iowa Oncology Research Association | Des Moines, Iowa 50309-1016 |
| CCOP - Duluth | Duluth, Minnesota 55805 |
| CCOP - Merit Care Hospital | Fargo, North Dakota 58122 |
| CCOP - Sioux Community Cancer Consortium | Sioux Falls, South Dakota 57105-1080 |
| CCOP - Bay Area Tumor Institute | Oakland, California 94609-3305 |
| CCOP - Geisinger Clinic and Medical Center | Danville, Pennsylvania 17822-2001 |
| CCOP - Marshfield Medical Research and Education Foundation | Marshfield, Wisconsin 54449 |
| Cancer Center and Beckman Research Institute, City of Hope | Duarte, California 91010-3000 |
| CCOP - Grand Rapids Clinical Oncology Program | Grand Rapids, Michigan 49503 |
| Children's Hospitals and Clinics - Minneapolis | Minneapolis, Minnesota 55404 |
| Children's Hospitals and Clinics of Minnesota | Saint Paul, Minnesota 55102 |
