Computerized Tomographic Colonography: Performance Evaluation in a Multicenter Setting
OBJECTIVES: I. Compare retrospectively the accuracy of computerized tomographic colonography
(CTC) vs pathology and colonoscopy in the detection of clinically important colorectal
neoplasia, defined as at least one proven lesion with a diameter measuring at least 1 cm.
II. Compare the physician image display preferences and interpretation time across three
viewing platforms for CTC images.
OUTLINE: This is a retrospective, multicenter study. Radiologists evaluate each patient's
optimal diagnostic computerized tomographic colonography (CTC) data. Patients' CTC findings
are evaluated by a radiologist at a central facility using an imaging display software
platform from General Electric, Vital Images, or the Mayo Clinic. CTC findings are compared
with conventional colonoscopy findings and pathologic analysis. A comparison is made between
physician image display preferences and interpretation time across three viewing platforms
for CTC images.
PROJECTED ACCRUAL: A total of 90 patients will be accrued for this study.
Interventional
Primary Purpose: Diagnostic
C. Daniel Johnson, MD
Study Chair
Mayo Clinic
United States: Federal Government
CDR0000067802
NCT00005809
July 2000
January 2003
Name | Location |
---|---|
Mayo Clinic Cancer Center | Rochester, Minnesota 55905 |
University of Alabama Comprehensive Cancer Center | Birmingham, Alabama 35294 |
Jonsson Comprehensive Cancer Center, UCLA | Los Angeles, California 90095-1781 |
Duke Comprehensive Cancer Center | Durham, North Carolina 27710 |
Comprehensive Cancer Center of Wake Forest University Baptist Medical Center | Winston-Salem, North Carolina 27157-1082 |
Milton S. Hershey Medical Center | Hershey, Pennsylvania 17033 |
NYU School of Medicine's Kaplan Comprehensive Cancer Center | New York, New York 10016 |
Mallinckrodt Institute of Radiology | Saint Louis, Missouri 63110 |
Boston Medical Center | Boston, Massachusetts 02118 |
Veterans Affairs Medical Center - San Francisco | San Francisco, California 94121 |
Emory University School of Medicine | Atlanta, Georgia 30322 |