The Utility of Positron Emission Tomography (PET) in Staging of Patients With Potentially Operable Carcinoma of the Thoracic Esophagus
OBJECTIVES:
- Determine the efficacy of fludeoxyglucose F 18 positron emission tomography imaging in
detecting lesions that would preclude esophagectomy in patients with carcinoma of the
thoracic esophagus or gastroesophageal junction.
OUTLINE: This is a multicenter study.
Patients receive fludeoxyglucose F 18 (FDG) IV followed 45-60 minutes later by positron
emission tomography (PET) imaging. Confirmatory studies, such as biopsy or other imaging
studies, are then conducted to confirm the FDG PET imaging results. Patients with no
metastases identified by FDG PET imaging may undergo esophagectomy with or without
neoadjuvant chemoradiotherapy within 1 month of evaluation.
Patients are followed within 6 months after surgery.
PROJECTED ACCRUAL: A total of 120-235 patients will be accrued for this study.
Interventional
Primary Purpose: Diagnostic
Bryan F. Meyers, MD, MPH
Study Chair
Washington University Siteman Cancer Center
United States: Federal Government
CDR0000067526
NCT00004867
November 1999
Name | Location |
---|---|
Memorial Sloan-Kettering Cancer Center | New York, New York 10021 |
Indiana University Cancer Center | Indianapolis, Indiana 46202-5265 |
Duke Comprehensive Cancer Center | Durham, North Carolina 27710 |
Massachusetts General Hospital Cancer Center | Boston, Massachusetts 02114 |
LDS Hospital | Salt Lake City, Utah 84143 |
University of Colorado Cancer Center at University of Colorado Health Sciences Center | Denver, Colorado 80010 |
Siteman Cancer Center at Barnes-Jewish Hospital | Saint Louis, Missouri 63110 |
Arthur G. James Cancer Hospital and Solove Research Institute at Ohio State University | Columbus, Ohio 43210-1240 |
Vanderbilt-Ingram Cancer Center at Vanderbilt Medical Center | Nashville, Tennessee 37232-2516 |
Allegheny General Hospital | Pittsburgh, Pennsylvania 15212-4772 |
UCSF Comprehensive Cancer Center | San Francisco, California 94115 |
Mobile Infirmary Medical Center | Mobile, Alabama 36640-0460 |
Swedish Cancer Institute at Swedish Medical Center - First Hill Campus | Seattle, Washington 98104 |
McDowell Cancer Center at Akron General Medical Center | Akron, Ohio 44307 |
Stanford Cancer Center at Stanford University Medical Center | Stanford, California 94305 |
Veterans Affairs Medical Center - Tennessee Valley Healthcare System - Nashville Campus | Nashville, Tennessee 37212 |
Comprehensive Cancer Center at University of Alabama at Birmingham | Birmingham, Alabama 35294 |
SUNY Upstate Medical University Hospital | Syracuse, New York 13210 |
Hollings Cancer Center at Medical University of South Carolina | Charleston, South Carolina 29425 |
Massey Cancer Center at Virginia Commonwealth University | Richmond, Virginia 23298-0037 |
Greenebaum Cancer Center at University of Maryland Medical Center | Baltimore, Maryland 21201 |
Jonsson Comprehensive Cancer Center at UCLA | Los Angeles, California 90095-1781 |
University of South Alabama Cancer Research Institute | Mobile, Alabama 36604 |
William Beaumont Hospital - Royal Oak | Royal Oak, Michigan 48073-6769 |
University of Tennessee, Memphis | Memphis, Tennessee 38163 |
Chao Family Comprehensive Cancer Center at University of California Irvine Medical Center | Orange, California 92868 |
Baylor University Medical Center | Dallas, Texas 75246 |
Providence Cancer Center at Providence Portland Medical Center | Portland, Oregon 97213-2967 |
Western Pennsylvania Cancer Institute at Western Pennsylvania Hospital | Pittsburgh, Pennsylvania 15224-1791 |
Morton Plant Hospital | Clearwater, Florida 33756 |
Tri-Health Good Samaritan Hospital | Cincinnati, Ohio 45220 |
Westmoreland Regional Hospital | Greensburg, Pennsylvania 15601-2282 |
St. Clair Memorial Hospital | Pittsburgh, Pennsylvania 15243-1899 |
Bethesda North Hospital | Cincinnati, Ohio 45242 |
Cancer Center at Greater Baltimore Medical Center | Baltimore, Maryland 21204 |