Trial Information
PROTOCOL OUTLINE: Data on the clinical course and growth rate of NF2-related tumors in
patients with neurofibromatosis 2. Patients are evaluated each year on a cranial and a
spinal MRI, eye tests, hearing tests, quality of life, neurological tests, and physical
functioning.
Inclusion Criteria
PROTOCOL ENTRY CRITERIA:
--Disease Characteristics--
- Diagnosed with neurofibromatosis 2 on or after 01/01/93
- Must meet one of the following conditions:
Bilateral vestibular schwannoma OR Family history of neurofibromatosis 2 (first degree
family relative) AND Unilateral vestibular schwannoma at under 30 years OR Any 2 of the
following: Meningioma Glioma Schwannoma Juvenile posterior subcapsular lenticular
opacity/juvenile cortical cataract
- No plans to treat vestibular schwannoma in next 12 months
--Prior/Concurrent Therapy--
- Not specified
--Patient Characteristics--
- Age: 5 and over
Type of Study:
Observational
Study Design:
Observational Model: Natural History, Time Perspective: Longitudinal
Principal Investigator
William H. Slattery, III
Investigator Role:
Study Chair
Investigator Affiliation:
House Ear Institute
Authority:
Unspecified
Study ID:
199/14226
NCT ID:
NCT00004483
Start Date:
January 2002
Completion Date:
Related Keywords:
- Schwannoma, Vestibular
- Neurofibromatosis 2
- Meningioma
- Meningioma
- Neurilemmoma
- Neurofibromatoses
- Neurofibromatosis 1
- Osteitis Fibrosa Cystica
- Neurofibromatosis 2
- Neuroma, Acoustic
Name | Location |
House Ear Institute |
Los Angeles, California 90057-9927 |