Study of Systemic Amyloidosis Presentation and Prognosis
N/A
N/A
Both
Amyloidosis
Trial Information
Study of Systemic Amyloidosis Presentation and Prognosis
PROTOCOL OUTLINE: Patients receive a comprehensive evaluation with an emphasis on
identifying prognostic and diagnostic factors. Assessments include gastrointestinal, renal,
hematologic, dermatologic, cardiac, and serologic studies. Immunologic studies include
antinuclear antibody, latex fixation, and serum and urine electrophoresis.
Genetic trees are constructed using detailed family history data; blood and urine samples
are routinely collected from relatives. Family members of patients with familial
amyloidotic polyneuropathy type II (Indiana type) undergo a flexor retinaculum biopsy of the
wrist.
Inclusion Criteria
PROTOCOL ENTRY CRITERIA:
--Disease Characteristics-- Systemic amyloidosis, i.e.: Primary, myeloma associated
Secondary, e.g., associated with the following conditions: Rheumatoid arthritis
Inflammatory bowel disease
Type of Study:
Observational
Study Design:
Primary Purpose: Screening
Principal Investigator
Merrill D. Benson
Investigator Role:
Study Chair
Investigator Affiliation:
Indiana University School of Medicine
Authority:
United States: Federal Government
Study ID:
NCRR-M01RR00750-0062
NCT ID:
NCT00004374
Start Date:
January 1979
Completion Date:
Related Keywords:
- Amyloidosis
- amyloidosis
- arthritis & connective tissue diseases
- genetic diseases and dysmorphic syndromes
- rare disease
- Amyloidosis
Name | Location |
|---|---|
| Indiana University Cancer Center | Indianapolis, Indiana 46202-5265 |
