An Evaluation of the Effect of Androgen Ablation on Bone Resorption in Prostate Cancer Patients

Inclusion Criteria

DISEASE CHARACTERISTICS:

- Histologically confirmed prostate cancer

- Stratum 1 (androgen ablation therapy):

- Bone metastases

- Prior orchiectomy allowed

- Prior or concurrent leuprolide and/or goserelin therapy allowed

- Stratum 2 (androgen ablation therapy):

- No bone metastases

- Prior orchiectomy allowed

- Prior or concurrent leuprolide and/or goserelin therapy allowed

- Stratum 3 (no androgen ablation therapy):

- No metastatic disease

- Prior flutamide or bicalutamide therapy allowed

PATIENT CHARACTERISTICS:

Age:

- Not specified

Performance status:

- Not specified

Life expectancy:

- Not specified

Hematopoietic:

- Calcium normal

Hepatic:

- Not specified

Renal:

- Not specified

PRIOR CONCURRENT THERAPY:

Biologic therapy:

- Not specified

Chemotherapy:

- See Disease Characteristics

Endocrine therapy:

- See Disease Characteristics

- No concurrent high dose steroids

Radiotherapy:

- Prior radiotherapy allowed

Surgery:

- See Disease Characteristics

- Prior radical prostatectomy allowed

Other:

- No concurrent bisphosphonates