Health Status and Quality of Life in Patients With Early Stage Hodgkin's Disease: A Companion Study to SWOG-9133

Trial Information

Health Status and Quality of Life in Patients With Early Stage Hodgkin's Disease: A Companion Study to SWOG-9133

OBJECTIVES: I. Evaluate prospectively the health status and quality of life of patients with
Stage I/IIA Hodgkin's disease randomized on protocol SWOG-9133 (CLB-9391) to treatment with
subtotal nodal irradiation with vs. without 3 courses of doxorubicin/vinblastine. II.
Describe the short-term effects of these treatments on these patients and compare their
impact on quality of life (i.e., patient symptom status, health status, fatigue). III.
Evaluate the intermediate and long-term effects of these treatments on these patients and
compare their impact on quality-of-life outcomes over 5 years.

OUTLINE: Quality-of-Life Assessment. Cancer Rehabilitation Evaluation System Short Form,
CARES-SF; Symptom and Personal Information Questionnaire (including Symptom Distress Scale,
MOS SF-36 Fatigue Scale, MOS SF-36 Health Perception Rating, Demographics); Cover Sheet.

PROJECTED ACCRUAL: Approximately 500 patients will be accrued over 7 years.