A Double-Blind Placebo-Controlled Study to Investigate the Action of Isoprinosine (Inosiplex) in Patients With Severe Acquired Immunodeficiency Syndrome

Inclusion Criteria

Exclusion Criteria

Co-existing Condition:

Patients with a history of gout, urolithiasis, nephrolithiasis, renal dysfunction, and
severe gastric ulcer are excluded.

Concurrent Medication:

Excluded:

- Steroids.

- Cytotoxic immunosuppressive agents.

- Radiotherapy.

The following are excluded:

- Critically ill patients.

- Patients receiving steroids, cytotoxic immunosuppressive agents, radiotherapy.

- Patients who have received any other immunotherapy.

- Patients with a history of gout, urolithiasis, nephrolithiasis, renal dysfunction,
and severe gastric ulcer.

Prior Medication:

Excluded:

- Any other immunotherapy.

Patients with severe AIDS and specified laboratory immunologic defects.