A Pilot Study To Evaluate Azidothymidine (AZT) in the Treatment of Human Immunodeficiency Virus (HIV) Infection in Patients Receiving a Bone Marrow Transplant

Inclusion Criteria

Exclusion Criteria

Co-existing Condition:

Patients with current life-threatening infection at time of transplant that would preclude
a transplant are excluded.

Concurrent Medication:

Excluded:

- Other anti-retroviral agents.

Patients with current life-threatening infection at time of transplant that would preclude
a transplant are excluded.

Patients must be:

- HTLV III antibody positive by ELISA or Western blot or HTLV III viremia.

- At high mortal risk with a diagnosis of AIDS or AIDS Related Complex (ARC).

- Also patient must fall into one of the following categories:

- Have an HIV seronegative identical twin to serve as a bone marrow donor.

- Have documentation of large cell/diffuse histiocytic lymphoma/DPDL.

- Be a good risk candidate for bone marrow transplant.