Inclusion Criteria

Patients age greater than or equal to 18 years.

Patients with histologically proven gastrointestinal adenocarcinoma, mesothelioma, or
sarcoma. By standard staging studies there must be evidence of advanced or metastatic
intraabdominal disease. Patients with minimal extraabdominal metastatic disease and who
have symptoms exclusively referable to advanced intraabdominal malignancy will be
considered for the study. Specifically, patients with gastric cancer and bulky N-2 lymph
node involvement or patients with other primaries and who have malignant ascites or
peritoneal seeding would be considered optimal candidates. If all gross peritoneal
disease is resected (i.e., gross omental implants removed by gastrectomy), patients are
still eligible for treatment.

Patients must have recovered from any toxicity from all prior chemotherapy, immunotherapy,
or radiotherapy (30 days).

Patients must not have any significant systemic illness (e.g., infection, cardiovascular,
or pulmonary) which would preclude them from being an operative candidate.

patients must have a life expectancy of at least 8 weeks.

Performance status should be ECOG level 0, 1, or 2.

Patients must have adequate renal function (i.e., serum creatinine less than or equal to
2.0 or creatinine clearance of greater than or equal to 45 ml/min).

Patients must be HIV negative.

Women of child bearing age must not be pregnant or breast feeding.

Patients with prior CDDP will be eligible if there is no evidence of existing irreversible
CDDP toxicity. Patients suspected of having chronic CDDP toxicity will be further
evaluated as clinically indicated.

Patients may have mild elevations (less than 2.0 times normal) in liver function test if
the abnormalities are consistent with advanced intra-abdominal cancer.

Abnormalities (greater than 1 sec over normal) in PT or PTT or severe thrombocytopenia
(less than 75 K) will render patients ineligible.

A low Hgb secondary to chronic tumor-related, blood loss is acceptable if the patient is
willing and able to have transfusion.

Patients will be ineligible if the WBC is less than 3,000.