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Diagnosis and Treatment of Pheochromocytoma


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Pheochromocytoma

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Trial Information

Diagnosis and Treatment of Pheochromocytoma


Patients suspected of having a pheochromocytoma will be studied via a series of tests in an
attempt to ascertain biochemically whether or not they really have such a tumor. These
procedures will include a standard clonidine suppression test and a standard glucagon
stimulation test. Once the diagnosis has been made on the basis of biochemistry, then
localization and therapy will be done via standard procedures. Measurement of plasma
metanephrines on mailed samples is available for physicians who seek further evidence for
the diagnosis of pheochromocytoma.

Inclusion Criteria


Patients of any age and either sex who are suspected of having a pheochromocytoma on the
basis of one or more of the following: 1. hypertensive episodes in a normotensive subject,
2. abnormal levels of blood and/or urinary catecholamines or their metabolites, or 3. an
otherwise unexplained abdominal mass.

Patients without any evidence of pheochromocytoma are excluded.

Type of Study:

Observational

Study Design:

N/A

Authority:

United States: Federal Government

Study ID:

880189

NCT ID:

NCT00001229

Start Date:

October 1988

Completion Date:

January 2001

Related Keywords:

  • Pheochromocytoma
  • Calcium-Pentagastrin
  • Clonidine
  • Glucagon
  • Pheochromocytoma
  • Pheochromocytoma

Name

Location
National Heart, Lung and Blood Institute (NHLBI) Bethesda, Maryland  20892