Trial Information

Evaluation of Patients With Thyroid Function Disorders

Patients with thyroid function abnormalities (hyperthyroidism, hypothyroidism) are studied
and

treated in this protocol. A limited number of patients with a personal history of signs,
symptoms or laboratory studies consistent with thyroid dysfunction or a strong family
history of thyroid abnormalities are also enrolled. Patients undergo routine history and
physical examination, standard endocrine blood and urine tests, a standard TRH test, thyroid
nuclear medicine scan, thyroidal radioiodine (RAI) or technetium (99mTc) uptake
measurements, as well as X-ray, computed tomography (CT) or magnetic resonance imaging (MRI)
studies or other standard diagnostic procedures, as clinically indicated. Patients will be
screened for entry into other research studies.