A Phase III Trial of Pelvic Radiation Therapy Versus Vaginal Cuff Brachytherapy Followed By Paclitaxel/Carboplatin Chemotherapy in Patients With High Risk, Early Stage Endometrial Carcinoma
OBJECTIVES:
Primary
- To compare the recurrence-free survival of patients with high-risk stage I or II
endometrial carcinoma treated with pelvic radiotherapy vs vaginal cuff brachytherapy,
paclitaxel, and carboplatin.
Secondary
- To compare survival of patients treated with these regimens.
- To compare patterns of failure in patients treated with these regimens.
- To compare physical functioning, fatigue, and neurotoxicity in patients treated with
these regimens.
- To correlate primary comorbid illnesses and obesity with survival, fatigue, and
physical functioning.
- To evaluate the psychometric properties (e.g., construct validity, reliability,
sensitivity to treatment, and responsiveness over time) of the PROMIS Fatigue-SF1.
- To evaluate fatigue measurement equivalence between patients with endometrial cancer
and age-matched women from the general population of the United States.
OUTLINE: This is a multicenter study. Patients are stratified according to extent of surgery
(hysterectomy and bilateral salpingo-oophorectomy without lymph node sampling, lymph node
dissection, or lymphadenectomy vs hysterectomy and bilateral salpingo-oophorectomy with
lymph node sampling, lymph node dissection, or lymphadenectomy). Patients with stage II
disease or stage I disease with a confirmed diagnosis of clear cell and/or papillary serous
histology who are randomized to arm I are also stratified according to intent to use vaginal
cuff brachytherapy (yes vs no). Patients are randomized to 1 of 2 treatment arms.
- Arm I: Patients undergo conventional or intensity-modulated pelvic radiotherapy once
daily, 5 days a week, for 5-6 weeks (total of 25-28 fractions) in the absence of
disease progression or unacceptable toxicity. Patients with stage II disease or stage I
disease with a confirmed diagnosis of clear cell and/or papillary serous histology may
also undergo 1 or 2 intravaginal (i.e., vaginal cuff) brachytherapy boost treatments.
- Arm II: Patients undergo vaginal cuff brachytherapy comprising 3-5 high-dose rate
brachytherapy treatments over approximately 2 weeks or 1 or 2 low-dose rate
brachytherapy treatments over 1-2 days. Beginning within 3 weeks after initiating
brachytherapy, patients receive paclitaxel IV over 3 hours and carboplatin IV over
30-60 minutes on day 1. Chemotherapy repeats every 21 days for up to 3 courses in the
absence of disease progression or unacceptable toxicity.
Patients complete questionnaires to assess quality of life, neurotoxicity, and fatigue at
baseline, 4 weeks, 10-11 weeks, 8 months, and 14 months.
After completion of study therapy, patients are followed periodically for up to 10 years.
Interventional
Allocation: Randomized, Primary Purpose: Treatment
Duration of recurrence-free survival
No
D. Scott McMeekin, MD
Study Chair
Oklahoma University Cancer Institute
Unspecified
CDR0000629591
NCT00807768
March 2009
Name | Location |
---|---|
National Naval Medical Center | Bethesda, Maryland 20889 |
Roswell Park Cancer Institute | Buffalo, New York 14263 |
Fred Hutchinson Cancer Research Center | Seattle, Washington 98109 |
Cardinal Bernardin Cancer Center at Loyola University Medical Center | Maywood, Illinois 60153-5500 |
MBCCOP - Hawaii | Honolulu, Hawaii 96813 |
University of Chicago Cancer Research Center | Chicago, Illinois 60637 |
Barbara Ann Karmanos Cancer Institute | Detroit, Michigan 48201 |
CCOP - Upstate Carolina | Spartanburg, South Carolina 29303 |
CCOP - Wichita | Wichita, Kansas 67214-3882 |
CCOP - Christiana Care Health Services | Wilmington, Delaware 19899 |
CCOP - Illinois Oncology Research Association | Peoria, Illinois 61602 |
CCOP - Iowa Oncology Research Association | Des Moines, Iowa 50309-1016 |
CCOP - Metro-Minnesota | Saint Louis Park, Minnesota 55416 |
Aurora Presbyterian Hospital | Aurora, Colorado 80012 |
Boulder Community Hospital | Boulder, Colorado 80301-9019 |
Penrose Cancer Center at Penrose Hospital | Colorado Springs, Colorado 80933 |
CCOP - Colorado Cancer Research Program | Denver, Colorado 80224-2522 |
Porter Adventist Hospital | Denver, Colorado 80210 |
Presbyterian - St. Luke's Medical Center | Denver, Colorado 80218 |
St. Joseph Hospital | Denver, Colorado 80218 |
Rose Medical Center | Denver, Colorado 80220 |
Swedish Medical Center | Englewood, Colorado 80110 |
St. Mary's Regional Cancer Center at St. Mary's Hospital and Medical Center | Grand Junction, Colorado 81502 |
Sky Ridge Medical Center | Lone Tree, Colorado 80124 |
Hope Cancer Care Center at Longmont United Hospital | Longmont, Colorado 80502 |
St. Mary - Corwin Regional Medical Center | Pueblo, Colorado 81004 |
North Suburban Medical Center | Thornton, Colorado 80229 |
Carole and Ray Neag Comprehensive Cancer Center at the University of Connecticut Health Center | Farmington, Connecticut 06360-2875 |
George Bray Cancer Center at the Hospital of Central Connecticut - New Britain Campus | New Britain, Connecticut 06050 |
Bronson Methodist Hospital | Kalamazoo, Michigan 49007 |
West Michigan Cancer Center | Kalamazoo, Michigan 49007-3731 |
Borgess Medical Center | Kalamazooaa, Michigan 49001 |
MeritCare Bemidji | Bemidji, Minnesota 56601 |
Fairview Ridges Hospital | Burnsville, Minnesota 55337 |
Mercy and Unity Cancer Center at Mercy Hospital | Coon Rapids, Minnesota 55433 |
Fairview Southdale Hospital | Edina, Minnesota 55435 |
Mercy and Unity Cancer Center at Unity Hospital | Fridley, Minnesota 55432 |
Minnesota Oncology Hematology, PA - Maplewood | Maplewood, Minnesota 55109 |
HealthEast Cancer Care at St. John's Hospital | Maplewood, Minnesota 55109 |
Hennepin County Medical Center - Minneapolis | Minneapolis, Minnesota 55415 |
Virginia Piper Cancer Institute at Abbott - Northwestern Hospital | Minneapolis, Minnesota 55407 |
St. Francis Cancer Center at St. Francis Medical Center | Shakopee, Minnesota 55379 |
Park Nicollet Cancer Center | St. Louis Park, Minnesota 55416 |
Regions Hospital Cancer Care Center | St. Paul, Minnesota 55101 |
United Hospital | St. Paul, Minnesota 55102 |
Ridgeview Medical Center | Waconia, Minnesota 55387 |
Minnesota Oncology Hematology, PA - Woodbury | Woodbury, Minnesota 55125 |
MeritCare Broadway | Fargo, North Dakota 58122 |
CCOP - MeritCare Hospital | Fargo, North Dakota 58122 |
Aultman Cancer Center at Aultman Hospital | Canton, Ohio 44710-1799 |
Case Comprehensive Cancer Center | Cleveland, Ohio 44106-5065 |
Abramson Cancer Center of the University of Pennsylvania | Philadelphia, Pennsylvania 19104-4283 |
Geisinger Medical Group - Scenery Park | State College, Pennsylvania 16801 |
Frank M. and Dorothea Henry Cancer Center at Geisinger Wyoming Valley Medical Center | Wilkes-Barre, Pennsylvania 18711 |
Sanford Cancer Center at Sanford USD Medical Center | Sioux Falls, South Dakota 57117-5039 |
Avera Cancer Institute | Sioux Falls, South Dakota 57105 |
Vanderbilt-Ingram Cancer Center | Nashville, Tennessee 37232-6838 |
University of Wisconsin Paul P. Carbone Comprehensive Cancer Center | Madison, Wisconsin 53792-6164 |
CCOP - Ochsner | New Orleans, Louisiana 70121 |
St. Joseph's Hospital and Medical Center | Phoenix, Arizona 85001-2071 |
Memorial Hospital of South Bend | South Bend, Indiana 46601 |
CCOP - Cancer Research for the Ozarks | Springfield, Missouri 65807 |
CCOP - Montana Cancer Consortium | Billings, Montana 59101 |
CCOP - Columbus | Columbus, Ohio 43206 |
CCOP - Greenville | Greenville, South Carolina 29615 |
University of Texas Medical Branch | Galveston, Texas 77555-1329 |
LDS Hospital | Salt Lake City, Utah 84143 |
Virginia Mason Medical Center | Seattle, Washington 98111 |
Rush University Medical Center | Chicago, Illinois 60612-3824 |
CCOP - Northern Indiana CR Consortium | South Bend, Indiana 46601 |
Saint Joseph Regional Medical Center | South Bend, Indiana 46617 |
Holden Comprehensive Cancer Center at University of Iowa | Iowa City, Iowa 52242-1002 |
UMASS Memorial Cancer Center - University Campus | Worcester, Massachusetts 01605-2982 |
Ellis Fischel Cancer Center at University of Missouri - Columbia | Columbia, Missouri 65203 |
Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill | Chapel Hill, North Carolina 27599-7570 |
Charles M. Barrett Cancer Center at University Hospital | Cincinnati, Ohio 45267-0526 |
Kimmel Cancer Center at Thomas Jefferson University - Philadelphia | Philadelphia, Pennsylvania 19107 |
UPMC Cancer Center at Magee-Womens Hospital | Pittsburgh, Pennsylvania 15213-3180 |
MultiCare Regional Cancer Center at Tacoma General Hospital | Tacoma, Washington 98405 |
Cancer Research Center of Hawaii | Honolulu, Hawaii 96813 |
MBCCOP - LSU Health Sciences Center | New Orleans, Louisiana 70112 |
CCOP - St. Louis-Cape Girardeau | Saint Louis, Missouri 63141 |
Brooke Army Medical Center | Fort Sam Houston, Texas 78234-6200 |
CCOP - Virginia Mason Research Center | Seattle, Washington 98101 |
Utah Valley Regional Medical Center - Provo | Provo, Utah 84604 |
Vince Lombardi Cancer Clinic at Aurora St. Luke's Medical Center | Milwaukee, Wisconsin 53201-2901 |
Rebecca and John Moores UCSD Cancer Center | La Jolla, California 92093-0658 |
Wesley Medical Center | Wichita, Kansas 67214 |
Fletcher Allen Health Care - University Health Center Campus | Burlington, Vermont 05401 |
John Stoddard Cancer Center at Iowa Methodist Medical Center | Des Moines, Iowa 50309 |
Kaiser Permanente Medical Center - San Francisco Geary Campus | San Francisco, California 94115 |
Kansas Masonic Cancer Research Institute at the University of Kansas Medical Center | Kansas City, Kansas 66160-7353 |
Josephine Ford Cancer Center at Henry Ford Hospital | Detroit, Michigan 48202 |
Swedish Cancer Institute at Swedish Medical Center - First Hill Campus | Seattle, Washington 98104 |
James Graham Brown Cancer Center at University of Louisville | Louisville, Kentucky 40202 |
Blumenthal Cancer Center at Carolinas Medical Center | Charlotte, North Carolina 28232-2861 |
Harry and Jeanette Weinberg Cancer Institute at Franklin Square Hospital Center | Baltimore, Maryland 21237 |
Hulston Cancer Center at Cox Medical Center South | Springfield, Missouri 65807 |
St. John's Regional Health Center | Springfield, Missouri 65804 |
UMDNJ University Hospital | Newark, New Jersey 07103 |
SUNY Downstate Medical Center | Brooklyn, New York 11203 |
Winthrop University Hospital | Mineola, New York 11501 |
McDowell Cancer Center at Akron General Medical Center | Akron, Ohio 44307 |
Lake/University Ireland Cancer Center | Mentor, Ohio 44060 |
Women and Infants Hospital of Rhode Island | Providence, Rhode Island 02905 |
Carilion Gynecologic Oncology Associates | Roanoke, Virginia 24014 |
Central Baptist Hospital | Lexington, Kentucky 40503 |
Long Island Jewish Medical Center | New Hyde Park, New York 11040 |
Kaiser Permanente Medical Center - Oakland | Sacramento, California 95825 |
Yale Cancer Center | New Haven, Connecticut 06520-8028 |
Advocate Christ Medical Center | Oak Lawn, Illinois 60453 |
Via Christi Cancer Center at Via Christi Regional Medical Center | Wichita, Kansas 67214 |
Ochsner Cancer Institute at Ochsner Clinic Foundation | New Orleans, Louisiana 70121 |
Alvin and Lois Lapidus Cancer Institute at Sinai Hospital | Baltimore, Maryland 21215 |
Hackensack University Medical Center Cancer Center | Hackensack, New Jersey 07601 |
Mount Sinai Medical Center | New York, New York 10029 |
Stony Brook University Cancer Center | Stony Brook, New York 11794-8174 |
SUNY Upstate Medical University Hospital | Syracuse, New York 13210 |
Presbyterian Cancer Center at Presbyterian Hospital | Charlotte, North Carolina 28233-3549 |
Wake Forest University Comprehensive Cancer Center | Winston-Salem, North Carolina 27157-1096 |
Simmons Comprehensive Cancer Center at University of Texas Southwestern Medical Center - Dallas | Dallas, Texas 75390 |
Lahey Clinic Medical Center - Burlington | Burlington, Massachusetts 01805 |
James P. Wilmot Cancer Center at University of Rochester Medical Center | Rochester, New York 14642 |
Sibley Memorial Hospital | Washington, District of Columbia 20016 |
St. Elizabeth Medical Center | Edgewood, Kentucky 41017 |
North Colorado Medical Center | Greeley, Colorado 80631 |
McKee Medical Center | Loveland, Colorado 80539 |
Saint Anthony's Hospital at Saint Anthony's Health Center | Alton, Illinois 62002 |
Good Samaritan Regional Health Center | Mt. Vernon, Illinois 62864 |
William Beaumont Hospital - Royal Oak Campus | Royal Oak, Michigan 48073 |
David C. Pratt Cancer Center at St. John's Mercy | St. Louis, Missouri 63141 |
Adena Regional Medical Center | Chillicothe, Ohio 54601 |
Riverside Methodist Hospital Cancer Care | Columbus, Ohio 43214 |
Strecker Cancer Center at Marietta Memorial Hospital | Marietta, Ohio 45750 |
Licking Memorial Cancer Care Program at Licking Memorial Hospital | Newark, Ohio 43055 |
Community Hospital of Springfield and Clark County | Springfield, Ohio 45505 |
Genesis - Good Samaritan Hospital | Zanesville, Ohio 43701 |
Utah Cancer Specialists at UCS Cancer Center | Salt Lake City, Utah 84106 |
Olympic Hematology and Oncology | Bremerton, Washington 98310 |
Skagit Valley Hospital Cancer Care Center | Mt. Vernon, Washington 98273 |
University Cancer Center at University of Washington Medical Center | Seattle, Washington 98195 |
Group Health Central Hospital | Seattle, Washington 98104 |
Greenebaum Cancer Center at University of Maryland Medical Center | Baltimore, Maryland 21201 |
Zimmer Cancer Center at New Hanover Regional Medical Center | Wilmington, North Carolina 28402-9025 |
University of South Alabama Mitchell Cancer Institute | Mobile, Alabama 36604 |
Samuel Oschin Comprehensive Cancer Institute at Cedars-Sinai Medical Center | Los Angeles, California 90048-1865 |
Jonsson Comprehensive Cancer Center at UCLA | Los Angeles, California 90095-1781 |
UCSF Helen Diller Family Comprehensive Cancer Center | San Francisco, California 94115 |
Kaiser Permanente Medical Center - Santa Clara Kiely Campus | Santa Clara, California 95051-5386 |
M.D. Anderson Cancer Center at Orlando | Orlando, Florida 32806 |
MBCCOP - Medical College of Georgia Cancer Center | Augusta, Georgia 30912-3730 |
Curtis and Elizabeth Anderson Cancer Institute at Memorial Health University Medical Center | Savannah, Georgia 31403-3089 |
Mountain States Tumor Institute at St. Luke's Regional Medical Center | Boise, Idaho 83712-6297 |
Advocate Lutheran General Cancer Care Center | Park Ridge, Illinois 60068-1174 |
Indiana University Melvin and Bren Simon Cancer Center | Indianapolis, Indiana 46202-5289 |
Lucille P. Markey Cancer Center at University of Kentucky | Lexington, Kentucky 40536-0093 |
Masonic Cancer Center at University of Minnesota | Minneapolis, Minnesota 55455 |
University of Mississippi Cancer Clinic | Jackson, Mississippi 39216-4505 |
Siteman Cancer Center at Barnes-Jewish Hospital - Saint Louis | St. Louis, Missouri 63110 |
Cancer Institute of New Jersey at UMDNJ - Robert Wood Johnson Medical School | New Brunswick, New Jersey 08903 |
University of New Mexico Cancer Center | Albuquerque, New Mexico 87131-5636 |
Don Monti Comprehensive Cancer Center at North Shore University Hospital | Manhasset, New York 11030 |
Herbert Irving Comprehensive Cancer Center at Columbia University Medical Center | New York, New York 10032 |
Oklahoma University Cancer Institute | Oklahoma City, Oklahoma 73104 |
Geisinger Cancer Institute at Geisinger Health | Danville, Pennsylvania 17822-0001 |
M. D. Anderson Cancer Center at University of Texas | Houston, Texas 77030-4009 |
Gundersen Lutheran Center for Cancer and Blood | La Crosse, Wisconsin 54601 |
Kaiser Permanente Medical Center - Sacramento | Sacramento, California 95825 |
Methodist Estabrook Cancer Center | Omaha, Nebraska 68114-4199 |
Chao Family Comprehensive Cancer Center at University of California Irvine Medical Center | Orange, California 92868 |
Huntsman Cancer Institute at University of Utah | Salt Lake City, Utah 84112 |
Robert H. Lurie Comprehensive Cancer Center at Northwestern University | Chicago, Illinois 60611 |
Todd Cancer Institute at Long Beach Memorial Medical Center | Long Beach, California 90801 |
Helen and Harry Gray Cancer Center at Hartford Hospital | Hartford, Connecticut 06102-5037 |
Elkhart General Hospital | Elkhart, Indiana 46515 |
Gynecologic Oncology of Indiana | Indianapolis, Indiana 46237 |
Howard Community Hospital | Kokomo, Indiana 46904 |
Maine Medical Center - Bramhall Campus | Portland, Maine 04102 |
Lakeland Regional Cancer Care Center - St. Joseph | St. Joseph, Michigan 49085 |
Fox Chase Virtua Health Cancer Program at Virtua Memorial Hospital Marlton | Marlton, New Jersey 08053 |
Hope A Women's Cancer Center | Asheville, North Carolina 28801 |
Mount Carmel Health - West Hospital | Columbus, Ohio 43222 |
Cancer Care Associates - Saint Francis Campus | Tulsa, Oklahoma 74136-1929 |
Rosenfeld Cancer Center at Abington Memorial Hospital | Abington, Pennsylvania 19001 |
Fox Chase Cancer Center - Philadelphia | Philadelphia, Pennsylvania 19111-2497 |
All Saints Cancer Center at Wheaton Franciscan Healthcare | Racine, Wisconsin 53405 |
Kaiser Permanente Medical Center - Hayward | Hayward, California 94545 |
Kaiser Permanente Medical Center - Redwood City | Redwood City, California 94063 |
Kaiser Permanente Medical Center - Richmond | Richmond, California 94801 |
Kaiser Permanente Medical Center - Roseville | Roseville, California 95661 |
South Sacramento Kaiser-Permanente Medical Center | Sacramento, California 95823 |
Kaiser Permanente Medical Center - Santa Teresa | San Jose, California 95119 |
Kaiser Foundation Hospital - San Rafael | San Rafael, California 94903 |
Kaiser Permanente Medical Center - Santa Rosa | Santa Rosa, California 95403 |
Kaiser Permanente Medical Center - South San Francisco | South San Francisco, California 94080 |
Kaiser Permanente Medical Facility - Stockton | Stockton, California 95210 |
Kaiser Permanente Medical Center - Walnut Creek | Walnut Creek, California 94596 |
John Muir/Mt. Diablo Comprehensive Cancer Center | Walnut Creek, California 94598 |
St. Joseph Medical Center | Bloomington, Illinois 61701 |
BroMenn Regional Medical Center | Normal, Illinois 61761 |
Community Cancer Center | Normal, Illinois 61761 |
Community Hospital of Ottawa | Ottawa, Illinois 61350 |
Oncology Hematology Associates of Central Illinois, PC - Ottawa | Ottawa, Illinois 61350 |
Oncology Hematology Associates of Central Illinois, PC - Peoria | Peoria, Illinois 61615 |
OSF St. Francis Medical Center | Peoria, Illinois 61637 |
Valley Cancer Center | Spring Valley, Illinois 61362 |
St. Francis Hospital and Health Centers - Beech Grove Campus | Beech Grove, Indiana 46107 |
Center for Cancer Therapy at LaPorte Hospital and Health Services | La Porte, Indiana 46350 |
John Stoddard Cancer Center at Iowa Lutheran Hospital | Des Moines, Iowa 50316-2301 |
Medical Oncology and Hematology Associates at John Stoddard Cancer Center | Des Moines, Iowa 50309 |
Medical Oncology and Hematology Associates at Mercy Cancer Center | Des Moines, Iowa 50314 |
Mercy Cancer Center at Mercy Medical Center - Des Moines | Des Moines, Iowa 50314 |
Medical Oncology and Hematology Associates - West Des Moines | West Des Moines, Iowa 50266 |
Cancer Center of Kansas, PA - Dodge City | Dodge City, Kansas 67801 |
Medical Center of Louisiana - New Orleans | New Orleans, Louisiana 70112 |
Feist-Weiller Cancer Center at Louisiana State University Health Sciences | Shreveport, Louisiana 71130-3932 |
Saint Francis Medical Center | Cape Girardeau, Missouri 63701 |
Cancer Institute of New Jersey at Cooper - Voorhees | Voorhees, New Jersey 08043 |
Highland Hospital of Rochester | Rochester, New York 14620 |
Samaritan North Cancer Care Center | Dayton, Ohio 45415 |
David L. Rike Cancer Center at Miami Valley Hospital | Dayton, Ohio 45409 |
Good Samaritan Hospital | Dayton, Ohio 45406 |
Blanchard Valley Medical Associates | Findlay, Ohio 45840 |
Charles F. Kettering Memorial Hospital | Kettering, Ohio 45429 |
UVMC Cancer Care Center at Upper Valley Medical Center | Troy, Ohio 45373-1300 |
Bryn Mawr Hospital | Bryn Mawr, Pennsylvania 19010 |
Lankenau Cancer Center at Lankenau Hospital | Wynnewood, Pennsylvania 19096 |
Dixie Regional Medical Center - East Campus | Saint George, Utah 84770 |
North Star Lodge Cancer Center at Yakima Valley Memorial Hospital | Yakima, Washington 98902 |
St. Anthony Central Hospital | Denver, Colorado 80204-1335 |
Exempla Lutheran Medical Center | Wheat Ridge, Colorado 80033 |
William W. Backus Hospital | Norwich, Connecticut 06360 |
Lancaster General Hospital | Lancaster, Pennsylvania 17604-3555 |
Palo Alto Medical Foundation | Palo Alto, California 94301 |
Northeast Georgia Medical Center | Gainesville, Georgia 30501 |
Mercy Cancer Center at Mercy Medical Center - North Iowa | Mason City, Iowa 50401 |
Regional Cancer Center at Singing River Hospital | Pascagoula, Mississippi 39581 |
UAB Comprehensive Cancer Center | Birmingham, Alabama 35294 |
Praxair Cancer Center at Danbury Hospital | Danbury, Connecticut 06810 |
Eastern Connecticut Hematology and Oncology Associates | Norwich, Connecticut 06360 |
Tunnell Cancer Center at Beebe Medical Center | Lewes, Delaware 19958 |
John B. Amos Cancer Center | Columbus, Georgia 31904 |
Evanston Hospital | Evanston, Illinois 60201-1781 |
Michiana Hematology-Oncology, PC - Elkhart | Elkhart, Indiana 46514 |
Elkhart Clinic, LLC | Elkhart, Indiana 46514-2098 |
Michiana Hematology Oncology PC - La Porte | La Porte, Indiana 46350 |
Michiana Hematology-Oncology, PC - South Bend | Mishawaka, Indiana 46545-1470 |
Michiana Hematology Oncology PC - Plymouth | Plymouth, Indiana 46563 |
Reid Hospital & Health Care Services | Richmond, Indiana 47374 |
McFarland Clinic, PC | Ames, Iowa 50010 |
Cancer Center of Kansas, PA - Chanute | Chanute, Kansas 66720 |
Cancer Center of Kansas, PA - El Dorado | El Dorado, Kansas 67042 |
Cancer Center of Kansas - Fort Scott | Fort Scott, Kansas 66701 |
Cancer Center of Kansas-Independence | Independence, Kansas 67301 |
Cancer Center of Kansas, PA - Kingman | Kingman, Kansas 67068 |
Lawrence Memorial Hospital | Lawrence, Kansas 66044 |
Cancer Center of Kansas, PA - Liberal | Liberal, Kansas 67905 |
Cancer Center of Kansas, PA - Newton | Newton, Kansas 67114 |
Menorah Medical Center | Overland Park, Kansas 66209 |
Saint Luke's Hospital - South | Overland Park, Kansas 66213 |
Cancer Center of Kansas, PA - Parsons | Parsons, Kansas 67357 |
Cancer Center of Kansas, PA - Pratt | Pratt, Kansas 67124 |
Cancer Center of Kansas, PA - Salina | Salina, Kansas 67401 |
Cancer Center of Kansas, PA - Wellington | Wellington, Kansas 67152 |
Cancer Center of Kansas, PA - Wichita | Wichita, Kansas 67214 |
Associates in Womens Health, PA - North Review | Wichita, Kansas 67208 |
Cancer Center of Kansas, PA - Medical Arts Tower | Wichita, Kansas 67208 |
Cancer Center of Kansas, PA - Winfield | Winfield, Kansas 67156 |
Greater Baltimore Medical Center Cancer Center | Baltimore, Maryland 21204 |
Michiana Hematology Oncology PC - Niles | Niles, Michigan 49120 |
Lakeside Cancer Specialists, PLLC | Saint Joseph, Michigan 49085 |
Willmar Cancer Center at Rice Memorial Hospital | Willmar, Minnesota 56201 |
St. Joseph Medical Center | Kansas City, Missouri 64114 |
North Kansas City Hospital | Kansas City, Missouri 64116 |
Saint Luke's Cancer Institute at Saint Luke's Hospital | Kansas City, Missouri 64111 |
Research Medical Center | Kansas City, Missouri 64132 |
Saint Luke's East - Lee's Summit | Lee's Summit, Missouri 64086 |
Liberty Hospital | Liberty, Missouri 64068 |
Heartland Regional Medical Center | Saint Joseph, Missouri 64506 |
Saint Joseph Oncology, Incorporated | Saint Joseph, Missouri 64507 |
Billings Clinic - Downtown | Billings, Montana 59107-7000 |
Great Falls Clinic - Main Facility | Great Falls, Montana 59405 |
Sletten Cancer Institute at Benefis Healthcare | Great Falls, Montana 59405 |
Monter Cancer Center of the North Shore-LIJ Health System | Lake Success, New York 11042 |
Summa Center for Cancer Care at Akron City Hospital | Akron, Ohio 44309-2090 |
Arthur G. James Cancer Hospital and Richard J. Solove Research Institute at Ohio State University Comprehensive Cancer Center | Columbus, Ohio 43210-1240 |
Mount Carmel St. Ann's Cancer Center | Westerville, Ohio 43081 |
Legacy Good Samaritan Hospital & Comprehensive Cancer Center | Portland, Oregon 97210 |
Northwest Cancer Specialists at Rose Quarter Cancer Center | Portland, Oregon 97227 |
St. Luke's Cancer Network at St. Luke's Hospital | Bethlehem, Pennsylvania 18015 |
Geisinger Hazleton Cancer Center | Hazleton, Pennsylvania 18201 |
Penn State Hershey Cancer Institute at Milton S. Hershey Medical Center | Hershey, Pennsylvania 17033-0850 |
McGlinn Family Regional Cancer Center at Reading Hospital and Medical Center | Reading, Pennsylvania 19612-6052 |
York Cancer Center at Apple Hill Medical Center | York, Pennsylvania 17405 |
Sandra L. Maxwell Cancer Center | Cedar City, Utah 84720 |
Jon and Karen Huntsman Cancer Center at Intermountain Medical Center | Murray, Utah 84157 |
Val and Ann Browning Cancer Center at McKay-Dee Hospital Center | Ogden, Utah 84403 |
Harrison Poulsbo Hematology and Onocology | Poulsbo, Washington 98370 |
Franciscan Cancer Center at St. Joseph Medical Center | Tacoma, Washington 98405-3004 |
Wenatchee Valley Medical Center | Wenatchee, Washington 98801-2028 |
Vince Lombardi Cancer Clinic - Green Bay at Aurora BayCare Medical Center | Green Bay, Wisconsin 54311 |
Aurora Medical Center | Summit, Wisconsin 53066 |
Vince Lombardi Cancer Clinic - Two Rivers | Two Rivers, Wisconsin 54241 |
Woman's Hospital | Baton Rouge, Louisiana 70815 |
Fox Chase Cancer Center CCOP Research Base | Philadelphia, Pennsylvania 19140 |
Seattle Cancer Care Alliance | Seattle, Washington 98109 |
Regional Cancer Center at Memorial Medical Center | Springfield, Illinois 62781-0001 |
Morton Plant Hospital | Clearwater, Florida 33756 |
John H. Stroger, Jr. Hospital of Cook County | Chicago, Illinois 60612-9985 |
Community Hospital | Munster, Indiana 46321 |
Methodist Hospital | Houston, Texas 77030 |
Aurora Sinai Medical Center | Milwaukee, Wisconsin 53201-0342 |
St. Joseph Hospital Regional Cancer Center - Orange | Orange, California 92868-3849 |
Radiological Associates of Sacramento Medical Group, Incorporated | Sacramento, California 95815 |
St. Vincent's Medical Center | Bridgeport, Connecticut 06606 |
Queen's Cancer Institute at Queen's Medical Center | Honolulu, Hawaii 96813 |
Elliot Regional Cancer Center at Elliot Hospital | Manchester, New Hampshire 03103 |
Tucker Center for Cancer Care at Orange Regional Medical Center | Middletown, New York 10940-4199 |
Bethesda North Hospital | Cincinnati, Ohio 45242 |
Gibbs Regional Cancer Center at Spartanburg Regional Medical Center | Spartanburg, South Carolina 29303 |
Union Hospital of Cecil County | Elkton MD, Maryland 21921 |
Duke Cancer Institute | Durham, North Carolina 27710 |
Cancer Centers of the Carolinas - Faris Road | Greenville, South Carolina 29605 |
Cancer Centers of the Carolinas - Seneca | Seneca, South Carolina 29672 |
Cancer Centers of the Carolinas - Spartanburg | Spartanburg, South Carolina 29307 |
Pacific Gynecology Specialists | Seattle, Washington 98104 |
Cancer Centers of the Carolinas - Eastside | Greenville, South Carolina 29601 |
MBCCOP - Meharry Medical College - Nashville | Nashville, Tennessee 37208-3599 |
Providence Cancer Center | Anchorage, Alaska 99508 |
Rockwood Clinic Cancer Treatment Center | Spokane, Washington 99204-2967 |
Solano Radiation Oncology Center | Vacaville, California 95687 |
Tyler Cancer Center | Tyler, Texas 75702 |
Gynecologic Oncology | Hinsdale, Illinois 60521 |
Women's Cancer Center - La Canada | Las Vegas, Nevada 89169 |
Good Samaritan Hospital Cancer Treatment Center | Cincinnati, Ohio 45220 |
Mercy General Hospital | Sacramento, California 95819 |
Valley Hospital - Ridgewood | Ridgewood, New Jersey 07450 |
United States Air Force Medical Center - Wright-Patterson | Wright-Patterson AFB, Ohio 45433-5529 |
Cancer Center of Paoli Memorial Hospital | Paoli, Pennsylvania 19301-1792 |
CCOP - Main Line Health | Wynnewood, Pennsylvania 19096 |
AnMed Cancer Center | Anderson, South Carolina 29621 |
U.T. Medical Center Cancer Institute | Knoxville, Tennessee 37920-6999 |
Fountain Valley, California 92708 | |
Olive View - UCLA Medical Center Foundation | Sylmar, California 91342 |
University of Colorado Cancer Center at UC Health Sciences Center | Aurora, Colorado 80045 |
Cancer Centers of North Carolina - Raleigh | Raleigh, North Carolina 27607 |
Jersey Shore Cancer Center at Jersey Shore University Medical Center | Neptune, New Jersey 07754-0397 |
Duke Health Raleigh Hospital | Raleigh, North Carolina 27609 |
Northwest Hospital and Medical Center | Seattle, Washington 98133 |
Cancer Care Center at John Muir Health - Concord Campus | Concord, California 94524-4110 |
Cancer Centers of the Carolinas - Greer Radiation Oncology | Greer, South Carolina 29650 |
Humphrey Cancer Center at North Memorial Outpatient Center | Robbinsdale, Minnesota 55422-2900 |
Lakeview Hospital | Stillwater, Minnesota 55082 |
West Texas Cancer Center | Odessa, Texas 79761 |
Central Georgia Gynecologic Oncology | Macon, Georgia 31201 |
Oncology Hematology Care, Incorporated - Blue Ash | Cincinnati, Ohio 45242 |
St. Mary Regional Cancer Center at St. Mary Medical Center | Walla Walla, Washington 99362 |
Auburn Radiation Oncology | Auburn, California 95603 |
Radiation Oncology Centers - Cameron Park | Cameron Park, California 95682 |
Radiation Oncology Center - Roseville | Roseville, California 95661 |
Harrison Medical Center | Bremerton, Washington 98310 |
Mercy Cancer Center at Mercy San Juan Medical Center | Carmichael, California 95608 |
Kaiser Permanente - Division of Research - Oakland | Oakland, California 94611 |
Rohnert Park Cancer Center | Rohnert Park, California 94928 |
CCOP - Kansas City | Prairie Village, Kansas 66208 |
St. Agnes Hospital Cancer Center | Baltimore, Maryland 21229 |
Renown Institute for Cancer at Renown Regional Medical Center | Reno, Nevada 89502 |
Sands Cancer Center | Canandiaqua, New York 14424 |
University Radiation Oncology at Parkridge Hospital | Rochester, New York 14626 |
Florida Gynecologic Oncology - Fort Myers | Fort Myers, Florida 33905 |
Gynecologic Oncology of West Michigan | Grand Rapids, Michigan 49546 |
Southwest Gynecologic Oncology Associates, Incorporated | Albuquerque, New Mexico 87102 |
Women's Cancer Care Associates | Albany, New York 12208 |
Black Hills Obstetrics & Gynecology LLP | Rapid City, South Dakota 57701 |
Aurora Women's Pavilion of West Allis Memorial Hospital | West Allis, Wisconsin 53227 |
Vince Lombardi Cancer Clinic - Oshkosh | Oshkosh, Wisconsin 54904 |
Roy and Patricia Disney Family Cancer Center at Providence Saint Joseph Medical Center | Burbank, California 91505 |
Tufts Medical Center Cancer Center | Boston, Massachusetts 02111 |
Longview Cancer Center | Longview, Texas 75601 |
Chattanooga GYN-Oncology | Chattanooga, Tennessee 37403 |
Central Dupage Cancer Center | Warrenville, Illinois 60555 |
University of New Mexico Cancer Center - South | Las Cruces, New Mexico 88011 |
Littleton Adventist Hospital | Littleton, Colorado 80122 |
Parker Adventist Hospital | Parker, Colorado 80138 |
Roger Maris Cancer Center at MeritCare Hospital | Fargo, North Dakota 58122 |
Central Indiana Cancer Centers - East | Indianapolis, Indiana 46219 |
Willamette Valley Cancer Center - Eugene | Eugene, Oregon 97401 |
Texas Oncology, PA at Harris Center HEB | Bedford, Texas 76022 |
Texas Oncology, PA at Texas Cancer Center - Denton South | Denton, Texas 76210 |
Klabzuba Cancer Center at Harris Methodist Fort Worth Hospital | Fort Worth, Texas 76104 |
Texas Oncology, PA at Texas Cancer Center - Sherman | Sherman, Texas 75090 |
Texas Oncology, PA at Texas Oncology Cancer Center Sugar Land | Sugar Land, Texas 77479 |
Women's Cancer Associates | Saint Petersburg, Florida 33701 |
New York Hospital Medical Center of Queens - Fresh Meadows | Fresh Meadows, New York 11365 |
Arizona Oncology - Tucson | Tucson, Arizona 85704 |
Arizona Cancer Center at University Medical Center North | Tucson, Arizona 85719 |
Adams Cancer Center | Gettysburg, Pennsylvania 17325 |
Cherry Tree Cancer Center | Hanover, Pennsylvania 17331 |
Providence Regional Cancer Partnership | Everett, Washington 98201 |
St. Vincent Oncology Center | Indianapolis, Indiana 46260 |
Texas Oncology, PA at Texas Cancer Center - Arlington South | Arlington, Texas 76014 |
All Saints Episcopal Hospital - Fort Worth | Fort Worth, Texas 76104 |
Leonard Lawson Cancer Center at Pikeville Medical Center | Pikeville, Kentucky 41501 |
Women's Institute for Gynecologic Cancer and Special Pelvic Surgery | Phillipsburg, New Jersey 08865 |
PeaceHealth Medical Group, PC at St. Joseph Hospital | Bellingham, Washington 98226 |
Olympic Medical Cancer Center | Sequim, Washington 98382 |